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Neuron 17:1157-1172

As can be seen in Table 8 these modification significantly increased the serum stability of dihexa in comparison to Nle'-AnglV

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However, it may play an anti-inflammatory and antioxidative role by directly affecting mitochondrial electron transport and neutralizing oxidative stress to alleviate mitochondrial damage, or by balancing intracellular environmental homeostasis and affecting the transcription of key regulatory proteins of inflammation (Ostojic, 2015)

In rare cases, more adverse side effects like kidney or liver dysfunction can occur

doi: 10.1016/j.cell.2024.05.031